Biomedical Research Grant Awardee 2024
Development of biosensor for non-invasive and early-stage detection of bladder cancer using urine samples
Dr Gopinath Packirisamy
Indian Institute of Technology Roorkee.
Bladder cancer is becoming more common and is now one of the top 11 cancers worldwide, according to the World Health Organization Cancer report. People who work with certain chemicals like those used in the dye and paint industries are at a higher risk, especially if they also smoke or have improper uro-hygiene. Scientists have discovered that urine from patients with bladder cancer contains specific substances, known as biomarkers, that may help to detect the disease in its preliminary stages. This project focuses on the promising biomarkers found in urine: one is a protein-based biomarker, and the other is a group of chemicals known as Volatile Organic Compounds (VOCs). The goal of this project is to develop a simple and accurate sensing unit that can detect these substances in urine. One will use a method similar to a home pregnancy test by the clinician, and the other will use a small sensing platform to detect the VOC chemicals. These tools could help doctors find bladder cancer earlier, making treatment more effective and saving lives.
Co-Investigators
Krishna Mohan Poluri
Professor, Department of Biosciences & Bioengineering, Joint faculty in centre for Nanotechnology, IIT Roorke
Devesh Bhimsaria
Assistant Professor, Department of Biosciences & Bioengineering, Joint Faculty in The Mehta Family School of Data Science & Artificial Intelligence (MFSDSAI),IIT Roorkee
Rajesh Kumar
Assistant Professor, Department of Biosciences & Bioengineering, IIT Roorkee
Clinical collaborator
Dr. Pankaj Kumar Garg
Professor & Head of the Department of Cancer Surgery, Shri Guru Ram Rai Institute of Medical & Health SSciences, Dehradun, Uttarkhand

