Biomedical Research Grant Awardee 2023

Nanorobotic system for oral health

Dr. Ambarish Ghosh

Indian Institute of Science, Bengaluru

Sharp pains in teeth while eating or drinking something hot or cold is a common problem faced by billions of people worldwide. It severely affects the quality of life and changes human eating habits due to pain.We are developing a permanent solution to this problem using experience from a decade of research in nanorobotics. We have developed CALBOTs – nanorobotic bioglass designed to fight sensitivity. CalBots are controlled by magnets and can travel deep inside human tooth, where they can form tiny plugs, sealing off the openings that cause sensitivity.

This is a new technology, but early results are promising. CALBOT treatment could offer a long-lasting solution for people with dental hypersensitivity, allowing them to enjoy hot and cold beverages without pain. We’ve tested CALBOTs in the lab and they’re showing great promise. They’re safe and effective, and could potentially offer a long-lasting solution for millions of people who suffer from tooth sensitivity. We expect this treatment to be available to masses in the near future.


Dr. Shanmukh Srinivas

IISc Bangalore and Theranautilus Pvt Ltd

Dr. Debayan Dasgupta

IISc Bangalore and Theranautilus Pvt Ltd

India is rapidly transforming into a dynamic hub of intellectual innovation and discovery. To support the science and technology ecosystem in the country, the Sree Padmavathi Venkateswara Foundation has created peer- reviewed funding programs that recognize exceptional researchers with the potential to achieve ground-breaking results in areas of critical national
importance. Our foundation provides these researchers with generous funding and empowering mentorship to generate knowledge and develop sustainable solutions of the highest quality, particularly in the fields of biomedical and agricultural research. We also work on projects to deploy advanced knowledge and improve the income of small and marginal farmers. We believe that by working together, we can create sustainable solutions that will benefit not only India but also the world.

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